* In a 1972 film version of Jack London's book, The Call of the Wild, which starred Charlton Heston.

* The Littlest Hobo was a live-action popular television series in the 1980's airing on CTV in Canada. It featured a German Shepherd that travelled from place to place, performing some good deed, and then moving on.

* Koton, a German Shepherd, stars as Jerry Lee, a police dog, in the 1989 movie K-9.

* From 1994 to 2005, the Austrian television show Kommissar Rex, (English Inspector Rex) featured a resourceful German Shepherd police dog.

* The manga Ginga Nagareboshi Gin and its sequel, Ginga Densetsu Weed have many German Shepherd characters, including the very popular black-and-white Shepherd, Jerome, and Gin's right-hand dog, John.
 

* In the 2000 film, The Cell, the antagonist of the film, a serial killer, owns an unusual, albino colored German Shepherd named Valentine, played by a dog named Tim.
 

* In the 2007 film, I Am Legend, a female German Shepherd named Abbey plays Sam (short for 'Samantha'), the companion of main character Robert Neville (played by Will Smith).
 

*Strongheart, also known as Etzel von Oeringen, was the first German Shepherd with name-above-the-title billing in a film. He starred in an adaptation of White Fang, released in 1925, and The Return of Boston Blackie, released in 1927.
 

*Buddy, a female German Shepherd, was the first formally trained guide dog in the United States. She belonged to Morris Frank, who worked to establish The Seeing Eye, the first dog guide school in America.
 

*Tulip, J. R. Ackerley's German shepherd, is the subject of Ackerley's My Dog Tulip.
 

* Horand von Grafrath, the first registered German Shepherd Dog
 

* Blondi, Adolf Hitler's German Shepherd
 

*Luks, Yugoslav President Josip Broz Tito's German Shepherd during the WW2. Luks saved Tito's life in the German invasion on Sutjeska (Bosnia). Tito was never without a dog. His first dog's name was Polak.
 

*Clipper, U.S. President John F. Kennedy's German Shepherd.